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Stephen Arnoff


Stephen C. Aronoff, MD, MBA


Waldo E. Nelson Chair, Department of Pediatrics

Professor, Pediatrics

Telephone: 215-707-6605

FAX: 215-707-5956

Email: stephen.aronoff@tuhs.temple.edu


Department of Pediatrics


Educational Background:


MD, University of Pittsburgh, Pittsburgh, PA, 1976


Internship, Pediatrics, Rainbow Babies and Children's Hospital, Cleveland, OH, 1977


Fellowship, Pediatrics, Rainbow Babies and Children's Hospital, Cleveland, OH, 1981

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clinical Interests:


  • Pediatric infectious diseases


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board certification(s):


  • Pediatrics
  • Pediatric Infectious Diseases

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professional affiliations:


  • American Academy of Pediatrics
  • Society of Pediatrics Research

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research interests:


  • Vaccine trials
  • Meta-analyses of common pediatric problems

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Recent Medically Related Publications, Obtained from PubMed (Click on PubMed ID to view abstract)

26589959. Gottesman LE, Del Vecchio MT, Aronoff SC, Etiologies of conjugated hyperbilirubinemia in infancy: a systematic review of 1692 subjects. BMC Pediatr 15:1(192)2015 Nov 20

26114743. Orlansky A, Smolij C, Moughan B, Aronoff SC, Factors that Affect Nonurgent Emergency Department Visits in a Publicly Insured Pediatric Population: An Observational Study. J Healthc Qual :()2015 Jun 25

25492164. Brower KS, Del Vecchio MT, Aronoff SC, The etiologies of non-CF bronchiectasis in childhood: a systematic review of 989 subjects. BMC Pediatr 14:(4)2014 Dec 10

25281186. England JT, Del Vecchio MT, Aronoff SC, Use of serum procalcitonin in evaluation of febrile infants: a meta-analysis of 2317 patients. J Emerg Med 47:6(682-8)2014 Dec

24697283. Barron SJ, Del Vecchio MT, Aronoff SC, Intravenous immunoglobulin in the treatment of Stevens-Johnson syndrome and toxic epidermal necrolysis: a meta-analysis with meta-regression of observational studies. Int J Dermatol 54:1(108-15)2015 Jan

23345983. Mikailov A, Kane I, Aronoff SC, Luck R, Delvecchio MT, Utility of adjunctive macrolide therapy in treatment of children with asthma: a systematic review and meta-analysis. J Asthma Allergy 6:(23-9)2013

21653620. Aronoff SC, How useful are laboratory tests in diagnosing serious infections in febrile children? BMJ 342:(d2782)2011 Jun 8

20563945. Aronoff SC, Evans B, Fleece D, Lyons P, Kaplan L, Rojas R, Integrating evidence based medicine into undergraduate medical education: combining online instruction with clinical clerkships. Teach Learn Med 22:3(219-23)2010 Jul

18321598. Isaacson G, Aronoff SC, Linezolid for tympanostomy tube otorrhea caused by methicillin-resistant Staphylococcus aureus and multiple drug-resistant Streptococcus pneumoniae. Int J Pediatr Otorhinolaryngol 72:5(647-51)2008 May

18174874. Flood RG, Badik J, Aronoff SC, The utility of serum C-reactive protein in differentiating bacterial from nonbacterial pneumonia in children: a meta-analysis of 1230 children. Pediatr Infect Dis J 27:2(95-9)2008 Feb

16991137. Paul SR, Hurford MT, Miettinen MM, Aronoff SC, Delvecchio M, Grewal H, Tuluc M, Polymorphous hemangioendothelioma in a child with acquired immunodeficiency syndrome (AIDS). Pediatr Blood Cancer 50:3(663-5)2008 Mar

16199713. Wooditch AC, Aronoff SC, Effect of initial corticosteroid therapy on coronary artery aneurysm formation in Kawasaki disease: a meta-analysis of 862 children. Pediatrics 116:4(989-95)2005 Oct

15520113. Fleece D, Gaughan JP, Aronoff SC, Griseofulvin versus terbinafine in the treatment of tinea capitis: a meta-analysis of randomized, clinical trials. Pediatrics 114:5(1312-5)2004 Nov

11445800. Tran D, Muchant DG, Aronoff SC, Short-course versus conventional length antimicrobial therapy for uncomplicated lower urinary tract infections in children: a meta-analysis of 1279 patients. J Pediatr 139:1(93-9)2001 Jul

10813089. Massengale AR, Quinn FJ, Williams A, Gallagher S, Aronoff SC, The effect of alginate on the invasion of cystic fibrosis respiratory epithelial cells by clinical isolates of Pseudomonas aeruginosa. Exp Lung Res 26:3(163-78)2000 Apr-May

10626126. Massengale AR, Ollar RA, Giordano SJ, Felder MS, Aronoff SC, Use of the paraffin wax baiting system for identification of Pseudomonas aeruginosa clinical isolates. Diagn Microbiol Infect Dis 35:3(177-83)1999 Nov

10511079. Prabhu VC, Kaufman HH, Voelker JL, Aronoff SC, Niewiadomska-Bugaj M, Mascaro S, Hobbs GR, Prophylactic antibiotics with intracranial pressure monitors and external ventricular drains: a review of the evidence. Surg Neurol 52:3(226-36; discussion 236-7)1999 Sep

10226079. Massengale AR, Quinn F Jr, Yankaskas J, Weissman D, McClellan WT, Cuff C, Aronoff SC, Reduced interleukin-8 production by cystic fibrosis airway epithelial cells. Am J Respir Cell Mol Biol 20:5(1073-80)1999 May

10210360. Elnicki DM, Halperin AK, Shockcor WT, Aronoff SC, Multidisciplinary evidence-based medicine journal clubs: curriculum design and participants' reactions. Am J Med Sci 317:4(243-6)1999 Apr

8677849. Aronoff SC, Antimicrobials in children and the problem of drug resistance. Am Fam Physician 54:1(44-6, 54, 56)1996 Jul

8649883. Lough DR, Ramadan HH, Aronoff SC, Acute suppurative thyroiditis in children. Otolaryngol Head Neck Surg 114:3(462-5)1996 Mar

7996376. Aronoff SC, Quinn FJ Jr, Carpenter LS, Novick WJ Jr, Effects of pentoxifylline on sputum neutrophil elastase and pulmonary function in patients with cystic fibrosis: preliminary observations. J Pediatr 125:6 Pt 1(992-7)1994 Dec

7921095. Pichichero ME, Gooch WM, Rodriguez W, Blumer JL, Aronoff SC, Jacobs RF, Musser JM, Effective short-course treatment of acute group A beta-hemolytic streptococcal tonsillopharyngitis. Ten days of penicillin V vs 5 days or 10 days of cefpodoxime therapy in children. Arch Pediatr Adolesc Med 148:10(1053-60)1994 Oct

1454442. Law DA, Aronoff SC, Anaerobic meningitis in children: case report and review of the literature. Pediatr Infect Dis J 11:11(968-71)1992 Nov

1722035. Aronoff SC, Quinn FJ Jr, Stern RC, Longitudinal serum IgG response to Pseudomonas cepacia surface antigens in cystic fibrosis. Pediatr Pulmonol 11:4(289-93)1991

2592859. Cohn RC, Aronoff SC, The effect of sodium on amiloride-tobramycin synergy in Pseudomonas cepacia. J Lab Clin Med 114:6(724-7)1989 Dec

2510122. Aronoff SC, The emergence of beta-lactam resistance among strains of Enterobacter cloacae and Pseudomonas aeruginosa. Pediatr Infect Dis J 8:9 Suppl(S100-3; discussion S128-32)1989 Sep

2552029. Jacobs MR, Aronoff SC, Appelbaum PC, Yamabe S, In vitro activity of YTR 830. J Chemother 1:3(151-4)1989 Jun

2855296. Aronoff SC, Outer membrane permeability in Pseudomonas cepacia: diminished porin content in a beta-lactam-resistant mutant and in resistant cystic fibrosis isolates. Antimicrob Agents Chemother 32:11(1636-9)1988 Nov

2452219. Aronoff SC, Stern RC, Serum IgG antibody to outer membrane antigens of Pseudomonas cepacia and Pseudomonas aeruginosa in cystic fibrosis. J Infect Dis 157:5(934-40)1988 May

3374992. Dickinson CJ, Reed MD, Stern RC, Aronoff SC, Yamashita TS, Blumer JL, The effect of exocrine pancreatic function on chloramphenicol pharmacokinetics in patients with cystic fibrosis. Pediatr Res 23:4(388-92)1988 Apr

3364958. Cohn RC, Jacobs M, Aronoff SC, In vitro activity of amiloride combined with tobramycin against Pseudomonas isolates from patients with cystic fibrosis. Antimicrob Agents Chemother 32:3(395-6)1988 Mar

3260021. Aronoff SC, Derepressed beta-lactamase production as a mediator of high-level beta-lactam resistance in Pseudomonas cepacia. Pediatr Pulmonol 4:2(72-7)1988

3118005. Aronoff SC, Olson MM, Gauderer MW, Jacobs MR, Blumer JL, Izant RJ Jr, Pseudomonas aeruginosa as a primary pathogen in children with bacterial peritonitis. J Pediatr Surg 22:9(861-4)1987 Sep

3104483. Aronoff SC, Shlaes DM, Factors that influence the evolution of beta-lactam resistance in beta-lactamase-inducible strains of Enterobacter cloacae and Pseudomonas aeruginosa. J Infect Dis 155:5(936-41)1987 May

3038003. Goldfarb J, Aronoff SC, Jaffe A, Reed MD, Blumer JL, Sultamicillin in the treatment of superficial skin and soft tissue infections in children. Antimicrob Agents Chemother 31:4(663-4)1987 Apr

3032883. Aronoff SC, Laurent C, Jacobs MR, In-vitro activity of erythromycin, roxithromycin and CP 62993 against common paediatric pathogens. J Antimicrob Chemother 19:2(275-6)1987 Feb

3331282. Rivkin MJ, Aronoff SC, Pulmonary infections in the immunocompromised child. Adv Pediatr Infect Dis 2:(161-80)1987

3540826. Chiesa C, Labrozzi PH, Aronoff SC, Decreased baseline beta-lactamase production and inducibility associated with increased piperacillin susceptibility of Pseudomonas cepacia isolated from children with cystic fibrosis. Pediatr Res 20:11(1174-7)1986 Nov

3492701. Aronoff SC, Labrozzi PH, Differences in drug susceptibility between isolates of Pseudomonas cepacia recovered from patients with cystic fibrosis and other sources and its relationship to beta-lactamase focusing pattern. Pediatr Pulmonol 2:6(368-72)1986 Nov-Dec

3026018. Aronoff SC, Scoles PV, Makley JT, Jacobs MR, Blumer JL, Kalamchi A, Efficacy and safety of sequential treatment with parenteral sulbactam/ampicillin and oral sultamicillin for skeletal infections in children. Rev Infect Dis 8 Suppl 5:(S639-43)1986 Nov-Dec

3774385. Reed MD, Aronoff SC, Stern RC, Yamashita TS, Myers CM, Friedhoff LT, Blumer JL, Single-dose pharmacokinetics of aztreonam in children with cystic fibrosis. Pediatr Pulmonol 2:5(282-6)1986 Sep-Oct

3019987. Aronoff SC, Jacobs MR, Labrozzi PH, Yamabe S, Synergy of amoxycillin combined with clavulanate and YTR 830 in experimental infections in mice. J Antimicrob Chemother 18:2(271-6)1986 Aug

3019984. Jacobs MR, Aronoff SC, Johenning S, Yamabe S, Comparative activities of the beta-lactamase inhibitors YTR 830, clavulanate and sulbactam combined with extended-spectrum penicillins against ticarcillin-resistant Enterobacteriaceae and pseudomonads. J Antimicrob Chemother 18:2(177-84)1986 Aug

3015017. Jacobs MR, Aronoff SC, Johenning S, Shlaes DM, Yamabe S, Comparative activities of the beta-lactamase inhibitors YTR 830, clavulanate, and sulbactam combined with ampicillin and broad-spectrum penicillins against defined beta-lactamase-producing aerobic gram-negative bacilli. Antimicrob Agents Chemother 29:6(980-5)1986 Jun

3928227. Elliott SJ, Aronoff SC, Clinical presentation and management of Pseudomonas osteomyelitis. Clin Pediatr (Phila) 24:10(566-70)1985 Oct

3879885. Klein BL, Boxerbaum B, Aronoff SC, Hemophilus influenzae type f meningitis in an adolescent. Pediatr Emerg Care 1:3(145-6)1985 Sep

4025253. Chiesa C, Pacifico L, Aronoff SC, Implication of Yersinia species in primary peritonitis. Am J Dis Child 139:8(751-2)1985 Aug

3161856. Klinger JD, Aronoff SC, In-vitro activity of ciprofloxacin and other antibacterial agents against Pseudomonas aeruginosa and Pseudomonas cepacia from cystic fibrosis patients. J Antimicrob Chemother 15:6(679-84)1985 Jun

3924879. Aronoff SC, Klinger JD, Comparison of cefpiramide (HR-810) and four anti-pseudomonal beta-lactam agents against pseudomonas isolates from children with cystic fibrosis. J Antimicrob Chemother 15:5(545-9)1985 May

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