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Xiaoying Deng, MD, PhD

Xiaoying Deng, MD, PhD

 

Assistant Professor, Clinical Medicine

Telephone: 215-707-1622

Email: xiaoying.deng@tuhs.temple.edu

 

Department of Medicine, Section of Hospitalist Medicine

 

 

Educational Background:

 

MD, West China University of Medical Sciences, Chengdu, Sichuan, China, 1987

 

PhD, Beijing Medical University, Beijing, China, 1993

 

Residency, Internal Medicine, Pennsylvania Hospital, Philadelphia, PA, 2008

 

Fellowship, Gastroenterology, University of Massachusetts, 2010

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Research Interests:

 

  • Brain-gut axis
  • Peptic ulcer disease
  • Regulatory peptides
  • Pancreatic exocrine secretion
  • Inflammation and fibrosis
  • Medical necessity and utilization review
  • Clinical research in hospital medicine

 

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board certification(s):

 

  • Internal Medicine

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professional affiliations:

 

  • American Gastroenterology Association, 1997
  • American Medical Association, 2005
  • Society of Hospital Medicine, 2013

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Books and Book Chapters:

 

Zhitian Zheng, Xiaoying Deng, Yubao Wang, Simao Ye, Li Zhang, Lianping Xing, Chunwei Huang, Yanfei Liu, Xiuyun Dong, Yunling Xu, Zhengying Wang, Yinong Li. Catecholamine and Peptic ulcer disease. Proceedings of 1995 Beijing Intemational Symposium on Peptic Ulcer Disease. pp: 63--66, 1995.

 

Xiaoying Deng, DC Whitcomb. Neurohormonal control of pancreatic exocrine secretion. Current Opinions in Gastroenterology 14(5): 362-368, 1998.

 

Xiaoying Deng. Ch 2. 13 Defensive Mechanism 2.13.1 Mucosal Circulation. In Peptic Ulcer Disease. People's Health Press, Beijing, China, 1998. pp: 213-231 (Chinese).

 

Xiaoying Deng. Ch 2.13 Defensive Mechanism 2.13.2 Mucus and Bicarbohydrate. In Peptic Ulcer Disease. People's Health Press, Beijing, China, 1998. pp: 232-259 (Chinese).

 

Xiaoying Deng, Zhi Tiang Zheng. Ch 2.13 Defensive Mechanism 2.13.3 Dopamine and Ulcer. In Peptic Ulcer Disease. People's Health Press, Beijing, China, 1998. pp: 259-286 (Chinese).

 

Gary B Glavin, Xiaoying Deng, Zhi Tiang Zheng. Ch 2.13 Defensive Mechanism 2.13.4 Dopamine and Peptic Ulcer Disease. In Peptic Ulcer Disease. People's Health Press, Beijing, China, 1998. pp: 287-293 (English with Chinese translation).

 

Boggiano MM, Chandler PC, Oswald KD, Rodgers RJ, Blundell JE, Ishii Y, Beattie AH, Holch P, Allison DB, Schindler M, Arndt K, Rudolf K, Mark M, Schoelch C, Joost HG, Klaus S, Thone-Reineke C, Benoit SC, Seeley RJ, Beck-Sickinger AG, Koglin N, Raun K, Madsen K, Wulff BS, Stidsen CE, Birringer M, Kreuzer OJ, Xiaoying Deng, Whitcomb DC, Hatem H, Taylor J, Dong J, Datta R, Culler M, Ortmann S, Castaneda TR, Tschop M. PYY 3-36 as an anti-obesity drug target. Obes Rev. 6(4): 307-22,2005. (UI: 16246216).

 

Xiaoying Deng and David C Whitcomb. Chapter 151. Pancreatic Polypeptide. In
Handbook of Biologically Active Peptides, Abba J. Kastin. Academic Press, 2006. pp: 1097-1107.

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PUBMED PUBLICATIONS :


Recent Medically Related Publications, Obtained from PubMed (Click on PubMed ID to view abstract)

25014191. Lin P, Yi Y, Lu M, Wang M, Yang Y, Lu Y, Song S, Zheng Z, Deng X, Zhang L, Heat shock protein 90 inhibitor mycoepoxydiene modulates kinase signaling in cervical cancer cells and inhibits in-vivo tumor growth. Anticancer Drugs 26:1(25-34)2015 Jan

16246216. Boggiano MM, Chandler PC, Oswald KD, Rodgers RJ, Blundell JE, Ishii Y, Beattie AH, Holch P, Allison DB, Schindler M, Arndt K, Rudolf K, Mark M, Schoelch C, Joost HG, Klaus S, Thöne-Reineke C, Benoit SC, Seeley RJ, Beck-Sickinger AG, Koglin N, Raun K, Madsen K, Wulff BS, Stidsen CE, Birringer M, Kreuzer OJ, Deng XY, Whitcomb DC, Halem H, Taylor J, Dong J, Datta R, Culler M, Ortmann S, Castañeda TR, Tschöp M, PYY3-36 as an anti-obesity drug target. Obes Rev 6:4(307-22)2005 Nov

15976389. Fortunato F, Deng X, Gates LK, McClain CJ, Bimmler D, Graf R, Whitcomb DC, Pancreatic response to endotoxin after chronic alcohol exposure: switch from apoptosis to necrosis? Am J Physiol Gastrointest Liver Physiol 290:2(G232-41)2006 Feb

15855815. Deng X, Wood PG, Eagon PK, Whitcomb DC, Rapid adaptation of pancreatic exocrine function to short-term alcohol feeding in rats. Pancreatology 5:2-3(183-95)2005

15632003. Deng X, Wang L, Elm MS, Gabazadeh D, Diorio GJ, Eagon PK, Whitcomb DC, Chronic alcohol consumption accelerates fibrosis in response to cerulein-induced pancreatitis in rats. Am J Pathol 166:1(93-106)2005 Jan

15259503. Deng X, Wood PG, Eagon PK, Whitcomb DC, Chronic alcohol-induced alterations in the pancreatic secretory control mechanisms. Dig Dis Sci 49:5(805-19)2004 May

15243972. Tschöp M, Castañeda TR, Joost HG, Thöne-Reineke C, Ortmann S, Klaus S, Hagan MM, Chandler PC, Oswald KD, Benoit SC, Seeley RJ, Kinzig KP, Moran TH, Beck-sickinger AG, Koglin N, Rodgers RJ, Blundell JE, Ishii Y, Beattie AH, Holch P, Allison DB, Raun K, Madsen K, Wulff BS, Stidsen CE, Birringer M, Kreuzer OJ, Schindler M, Arndt K, Rudolf K, Mark M, Deng XY, Whitcomb DC, Halem H, Taylor J, Dong J, Datta R, Culler M, Craney S, Flora D, Smiley D, Heiman ML, Physiology: does gut hormone PYY3-36 decrease food intake in rodents? Nature 430:6996(1 p following 165; discussion 2 p following 165)2004 Jul 8

11713954. Deng X, Guarita DR, Pedroso MR, Wood PG, Kreiss C, Sved AF, Whitcomb DC, Area postrema lesion alters the effects of peptide YY on 2-DG-stimulated pancreatic exocrine secretion. Dig Dis Sci 46:11(2460-9)2001 Nov

11484913. Li HS, Deng XY, Thompson BS, Zhang JY, Wood PG, Eagon PK, Whitcomb DC, Chronic ethanol consumption induces gene expression of pancreatic monitor peptide, but not SPINK1/PSTI-56, in rats. Pancreas 23:2(117-24)2001 Aug

11459924. Li HS, Zhang JY, Thompson BS, Deng XY, Ford ME, Wood PG, Stolz DB, Eagon PK, Whitcomb DC, Rat mitochondrial ATP synthase ATP5G3: cloning and upregulation in pancreas after chronic ethanol feeding. Physiol Genomics 6:2(91-8)2001 Jul 17

11448870. Deng X, Guarita DR, Pedroso MR, Kreiss C, Wood PG, Sved AF, Whitcomb DC, PYY inhibits CCK-stimulated pancreatic secretion through the area postrema in unanesthetized rats. Am J Physiol Regul Integr Comp Physiol 281:2(R645-53)2001 Aug

11376591. Deng X, Wood PG, Sved AF, Whitcomb DC, The area postrema lesions alter the inhibitory effects of peripherally infused pancreatic polypeptide on pancreatic secretion. Brain Res 902:1(18-29)2001 May 25

11270780. Deng X, Guarita DR, Wood PG, Kriess C, Whitcomb DC, PYY potently inhibits pancreatic exocrine secretion mediated through CCK-secretin-stimulated pathways but not 2-DG-stimulated pathways in awake rats. Dig Dis Sci 46:1(156-65)2001 Jan

11052307. Guarita DR, Deng X, Huh YB, Wood PG, Reeve JR Jr, Whitcomb DC, PYY regulates pancreatic exocrine secretion through multiple receptors in the awake rat. Dig Dis Sci 45:9(1696-702)2000 Sep

9596939. Deng X, Zheng Z, Ye S, [Localization and expression of dopamine receptors in stomach and duodenum in rats]. Zhonghua Yi Xue Za Zhi 77:2(103-5)1997 Feb

9388998. Deng X, Gen Q, Zheng Z, [Monoamine concentrations in experimental ulcers in rats]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 18:3(229-33)1996 Jun

7835142. Deng XY, Zheng ZT, [An animal model of peptic ulcer induced by destruction of dopaminergic neurons]. Zhonghua Nei Ke Za Zhi 33:5(313-6)1994 May

2094644. Deng X, Wu Y, Zhang J, [Primary study on pathogenesis of Campylobacter jejuni enteritis]. Hua Xi Yi Ke Da Xue Xue Bao 21:4(427-9)1990 Sep